Gabapentin tablets are used to prevent and control partial seizures and relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. It is available as an oral capsule, an immediate-release oral tablet, and an extended-release oral tablet. It’s also available as a generic drug. You can purchase generic drugs less than the brand-name version in cost.

Gabapentin is a medicine used to treat partial seizures and nerve pain from shingles. It acts on the chemical messengers in the brain and nerves. It is a group of medicines called anticonvulsants.

Side effects consist of:

Gabapentin can slow or stop breathing especially if you have taken an opioid medication or alcohol. Some of the common side effects that can occur with use of gabapentin are listed below:

·         Viral infection

·         Fever

·         Nausea and vomiting

·         Trouble speaking

·         Hostility

·         Jerky movements

Dosing information

Usual Adult Dosage:

Initial Dose: 300 mg orally once a day, 300 mg orally 2 times a day on the second day, and then 300 mg orally 3 times a day on the third day.

Maintenance dose: 300 to 600 mg taken orally 3 times a day.

Maximum dose: 600 mg taken orally daily in 3 divided doses.

Mechanism of Action

Gabapentin is structurally similar to the neurotransmitter GABA but it cannot modify GABA binding and is not converted metabolically into GABA or GABA agonists and it is not an inhibitor of GABA uptake. GABA can reduce the excitability of nerve cells in the brain, which acts in seizures and the transmission of pain signals.

Drug Interactions

If you are taking any other medicines including medicines for epilepsy or seizures,  warfarin, birth control pills, chloramphenicol, metronidazole, and doxycycline, medicines to control viral infection (e.g., nelfinavir), asthma medicines (e.g., theophylline and montelukast).

Take advice from a doctor if you are planning to become pregnant or are breastfeeding. Further, you should consult with the doctor if you have ever had liver problems, kidney problems, or lung problems.

When and how does Gabapentin help?

Gabapentin is used as a Pain Relief Tablet to relieve nerve pain in conditions like postherpetic neuralgia, a chronic pain condition in people who have had shingles.

It’s not clear how gabapentin acts, but it seems to reduce unusual excitement in the brain for people with seizures and helps in reducing pain by changing how the body senses pain. Gabapentin is also taken for the treatment of diabetic neuropathy, trigeminal neuralgia facial pain, generalized anxiety disorder, hot flashes, and chronic lower back pain. 

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