Pain Relief Tablets

Oxycodone is an opioid pain medication that comes under the category of a narcotic. It can cause physical dependence and addiction. The oxycodone to morphine dose combination ratio is approximately 1 to 1.5 for immediate-release and 1 to 2 for extended-release formulations. When Oxycodone Pills are taken for a long duration, it may become habit-forming, causing mental or physical dependence.

However, people who have pain for a long duration should not let the fear of dependence keep them from using narcotics to relieve pain. Mental dependence (addiction) is not likely to occur on using narcotics for this purpose. Physical dependence may cause withdrawal side effects if treatment is stopped suddenly.

Side Effects

Oxycodone can slow or stop your breathing, and death may occur, take advice from the doctor before taking it.

·         constipation

·         nausea

·         somnolence

·         dizziness

·         vomiting

·         pruritus

·         headache

·         dry mouth

·         asthenia


Using narcotics drug for a long time can cause severe constipation

This medicine may cause sleep-related breathing problems (hypoxemia)

The medicine will add to the effects of alcohol and other CNS depressants (antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics). This effect may last for a few days after stopping using this medicine. 

Oxycodone Dosage

The Oxycodone doses will be different for different persons. The doses of medicine depend on the strength of the medicine.

For oral dosage form (tablets):

For moderate to severe pain:

Adults—Every dose of 5 to 15 milligrams (mg) must be taken in 4 to 6 hours.

The dosage of the children must be determined by the doctor or specialist to avoid side effects.

Oxycodone 30 mg

Oxycodone 30 mg is metabolized in the liver into noroxycodone, oxymorphone, and noroxymorphone. Noroxycodone and noroxymorphone are the main circulating metabolites. Noroxycodone is a weak mu opioid agonist and Noroxymorphone has potent mu-opioid agonist properties, both these metabolites do not cross the blood-brain barrier to a significant extent. Oxymorphone is a potent mu-opioid agonist but is present in a very low concentration after oxycodone administration.

Mechanism of Action

Oxycodone is an opioid agonist and is relatively selective on the mu receptor, although it also can bind to other opioid receptors. The main therapeutic action of oxycodone is analgesia. The accurate mechanism of the analgesic action is unknown. However, specific CNS opioid receptors for endogenous compounds with opioid-like activity have been identified in the brain and spinal cord and seem to play a role in the analgesic effects of this drug.

Oxycodone has a significantly lower affinity on the μ-opioid receptor compared with morphine. It is a potent opioid, comparable to morphine.

Pain Relief Tablets

Oxycodone is used as a Pain Relief Tablet. Any single analgesic drug is not effective in every pain condition. In addition to convenience and possibly improved compliance, a combination of analgesic drugs, provides greater pain relief and reduced adverse effects than the constituent drugs when used individually. The analgesic or adverse effect profiles of the combinations (with acetaminophen, paracetamol, nonsteroidal anti-inflammatory drugs, morphine, gabapentin, or pregabalin) are effective in pain relief.